Thermo Fisher Scientific FABP5 Polyclonal Antibody

Applications and Tested Dilution

Product Specifications

Product Specific Information

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.

Target Information

FABP5 (fatty acid binding protein 5, psoriasis-associated) is encoded by the FABP5 gene, also known as PAFABP, EFABP, E-FABP, KFABP, PA-FABP, and Epidermal-type fatty acid-binding protein.
It belongs to a family of small, highly conserved cytoplasmic proteins that bind long-chain fatty acids and hydrophobic ligands.
The PAFABP cDNA encodes a 135-amino acid protein with a molecular weight of approximately 15,164 Da.
FABP5 is primarily expressed in epidermal cells and was first identified as being upregulated in psoriatic tissue.
Its roles include fatty acid uptake, transport, and metabolism.
Kaczocha et al. (2009) identified FABP5 and FABP7 as cytosolic proteins that transport AEA from the plasma membrane to subcellular fatty acid amide hydrolase, where it is hydrolyzed and inactivated. FABP3 did not show this specific transport function.

Safety Information

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.