Thermo Fisher Scientific ARAP1 Polyclonal Antibody
ARAP1 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체. Western blot 및 IHC(P)에서 사용 가능. Human 및 Mouse 반응성. Goat 유래 IgG, 비결합형 액상 항체로 -20°C 보관. 연구용으로만 사용.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | Assay-dependent |
| Immunohistochemistry (Paraffin) (IHC (P)) | 6–8 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence C-AFTADPLSLLRNV |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Wet ice |
| RRID | AB_2932735 |
Product Specific Information
This antibody is expected to recognize isoform a (NP_056057.2), isoform c (NP_001035207.1), and isoform d (NP_001128662.1).
Tested in Peptide ELISA: antibody detection limit dilution 1:32,000.
Target Information
ARAP1 (angiotensin II type 1 receptor-associated protein) is an adaptor protein with ArfGAP and RhoGAP activities, containing five PH domains and ankyrin repeats.
This adaptor serves as a link between phosphoinositide-, Arf-, and Rho-mediated cell signaling.
ARAP1 supports plasma membrane recycling of angiotensin II type 1 receptor (AT1) and contributes to cell-specific trafficking of pro-death receptor TRAIL-R1 (DR4), promoting TRAIL-induced apoptosis in certain cell types.
It also affects cell spreading.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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