Thermo Fisher Scientific TRPM8 Polyclonal Antibody
TRPM8 단백질을 인식하는 Rabbit Polyclonal 항체로, WB 및 IHC에 적합합니다. Rat TRPM8 유래 합성 펩타이드를 면역원으로 사용하였으며, 비결합형 동결건조 형태로 제공됩니다. 단기 4°C, 장기 -20°C 보관을 권장합니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500 | - |
| Immunohistochemistry (IHC) | 1:500 | - |
| Miscellaneous PubMed (Misc) | - | View 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from rat TRPM8, conjugated to blue carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of sterile water.
- Centrifuge to remove any insoluble material.
- Specificity: TRPM8.
Target Information
TRPM8 is a receptor-activated non-selective cation channel involved in the detection of cool sensations, activated by temperatures below 25°C as well as compounds such as icilin, eucalyptol, and menthol. It is permeable to monovalent cations (Na⁺, K⁺, Cs⁺) and divalent cation (Ca²⁺).
TRPM8 expression is mainly observed in prostate epithelial cells, with moderate expression in normal prostate tissue and elevated levels in prostate cancer. TRPM8 mRNA has also been detected in various nonprostatic tumors (breast, colon, lung, skin), but rarely in corresponding normal tissues.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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