Thermo Fisher Scientific L3MBTL1 Polyclonal Antibody
L3MBTL1 단백질을 인식하는 Rabbit Polyclonal 항체로 Western blot에 최적화되어 있습니다. 인간, 마우스, 랫 등 다양한 종에 반응하며, 친화 크로마토그래피로 정제되었습니다. PBS 버퍼에 보관되며 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 0.2–1.0 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the middle region of human L3MBTL1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2688883 |
Product Specific Information
This target displays homology in the following species:
- Dog: 77%
- Guinea Pig: 93%
- Horse: 92%
- Human: 85%
- Mouse: 100%
- Rabbit: 85%
- Rat: 100%
Target Information
L3MBTL1 is the homolog of a protein identified in Drosophila as a suppressor of malignant transformation of neuroblasts and ganglion-mother cells in the optic centers of the brain.
L3MBTL1 localizes to condensed chromosomes in mitotic cells, and its overexpression in glioma cell lines causes improper nuclear segregation and cytokinesis, producing multinucleated cells.
It represents a polycomb group gene regulating gene activity, likely via chromatin modification. The protein specifically recognizes and binds mono- and dimethyllysine residues on target proteins, acting as a reader of post-translational modifications.
Alternatively spliced transcript variants encoding different isoforms of the L3MBTL1 gene have been identified.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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