
Thermo Fisher Scientific JAB1 Recombinant Rabbit Monoclonal Antibody (JB34-96)
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Applications
Tested Dilution
Publications
Western Blot (WB)
1:500
Immunohistochemistry (Paraffin) (IHC (P))
1:50-1:200
Immunocytochemistry (ICC/IF)
1:100-1:500
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit / IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
JB34-96
Immunogen
Recombinant protein within Human JAB1 aa 1-140 if (typeof window.$mangular === undefined
|| !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{
targetFamily:
JAB1,
uniProtId:
Q92905-1,
ncbiNodeId:
9606,
antigenRange:
1-140,
antigenLength:
334,
antigenImageFileName:
MA5-34666_JAB1_Q92905-1_Rabbit.svg,
antigenImageFileNamePDP:
MA5-34666_JAB1_Q92905-1_Rabbit_PDP.jpeg,
sortOrder:
1}\]
; $mangular.isB2BCMGT = false
; $mangular.isEpitopesModalImageMultiSizeEnabled = true
;
View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}
Conjugate
Unconjugated Unconjugated Unconjugated
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
TBS, pH 7.4, with 40% glycerol, 0.05% BSA
Contains
0.05% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles, store in dark
Shipping conditions
Wet ice
RRID
AB_2848574
Product Specific Information
Positive Control: A431, A549, PC-3M, rat brain tissue, human kidney tissue, mouse testis tissue.
Target Information
JAB-1 is a 38 kDa protein which was originally described as a coactivator for cJUN. It is present in a large protein complex called the Signalosome
, which has been proposed to play a signaling role in mammalian cells. This protein complex appears to be analogous to the COP9 complex in plants, which is important in light-mediated plant development. Although the specific function of JAB-1 in this complex is unclear, it has recently been implicated in targeting proteins for degradation by the proteasome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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