Thermo Fisher Scientific PSMB9 Recombinant Rabbit Monoclonal Antibody (JB35-07)
Rabbit monoclonal antibody recognizing human PSMB9 (LMP2). Validated for WB, IHC-P, and Flow Cytometry. Recombinant expression in HEK293 cells ensures high specificity and reproducibility. Supplied as liquid, 1 mg/mL, Protein A purified, suitable for r...
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:50–1:200 |
| Flow Cytometry (Flow) | 1:50–1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | JB35-07 |
| Immunogen | Recombinant protein within Human Proteasome 20S LMP2 (aa 85–219) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 40% glycerol, 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, avoid freeze/thaw cycles, store in dark |
| Shipping Conditions | Wet ice |
| RRID | AB_2848575 |
Product Specific Information
- Positive Control: U937, mouse colon tissue lysate, human spleen tissue, Daudi.
Target Information
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure composed of four rings of 28 non-identical subunits. Two rings consist of seven alpha subunits and two rings of seven beta subunits. Proteasomes are abundant in eukaryotic cells and cleave peptides in an ATP/ubiquitin-dependent, non-lysosomal pathway. The immunoproteasome plays an essential role in processing class I MHC peptides.
This gene encodes a member of the proteasome B-type (T1B) family, a 20S core beta subunit located in the class II region of the MHC. Proteolytic processing is necessary to produce the mature subunit.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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