
Thermo Fisher Scientific FEZ2/Zygin2 Polyclonal Antibody
FEZ2/Zygin2 단백질을 인식하는 Rabbit Polyclonal 항체로 Western blot, IHC, ICC, ELISA 등 다양한 응용에 적합합니다. Human, Mouse, Rat에서 반응하며 Protein A로 정제된 액상 형태입니다. 연구용으로 세포 형태 변화 연구에 활용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:50–1:200 |
| Immunohistochemistry (Frozen) (IHC-F) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide derived from human FEZ2/Zygin2 (amino acids 165–240) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Fasciculation and elongation protein zeta-2 (FEZ2) is a homolog of mammalian FEZ1, which is an ortholog of C. elegans UNC-76. Unlike FEZ1, FEZ2 mRNA is widely expressed in mouse tissues. FEZ2 interacts with protein kinase C (PKC)-zeta substrate and induces neurite extension of PC12 cells when co-expressed with a constitutively active form of PKC-zeta, suggesting that FEZ2 may play an important role in morphological changes of various cells by associating with PKC-zeta in a tissue-non-specific manner. FEZ2 can also interact with FEZ1 through its C-terminal regions, particularly its coiled-coil region. At least two isoforms of FEZ2 are known to exist.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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