Thermo Fisher Scientific Galectin 12 Polyclonal Antibody
돼지 Galectin-12 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체. WB, IHC, ICC/IF에 사용 가능하며, 고순도 Protein A 정제 제품. PBS/glycerol 버퍼에 보관하며 연구용으로만 사용.
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Thermo Fisher Scientific Galectin 12 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.5–2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC-P) | 5–20 µg/mL |
| Immunocytochemistry (ICC/IF) | 5–20 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Pig |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Pig GAL12 protein, Met1–Tyr314 (Accession #B7U2G9) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.05% Proclin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3090426 |
Target Information
Galectin-12, also designated galectin-related inhibitor of proliferation 1 in mouse, is a 314 amino acid protein encoded by the human gene LGALS12. It belongs to the galectin family, which consists of β-galactoside-binding proteins with conserved carbohydrate recognition domains.
Galectin-12 binds lactose and may participate in adipocyte apoptosis. This protein is preferentially expressed in peripheral blood leukocytes and adipocytes.
It is induced by cell cycle block at the G1 phase and causes G1 arrest when overexpressed. The galectin-12 gene is expressed in mouse preadipocytes and is upregulated during cell cycle arrest, coinciding with differentiation competence in response to adipogenic hormone stimulation.
Galectin-12 is an adipocyte-expressed protein that is downregulated by insulin resistance-inducing hormones, suggesting a role in the pathogenesis of insulin resistance.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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