Thermo Fisher Scientific SCFD1 Monoclonal Antibody (OTI1E2), TrueMAB

Applications

• Western Blot (WB): 1:500–1:2,000

Species Reactivity

• Dog
• Human
• Mouse
• Rat

Host / Isotype

• Mouse / IgG1

Class

• Monoclonal

Type

• Antibody

Clone

• OTI1E2

Immunogen

Full length human recombinant protein of human SCFD1 produced in HEK293T cell.

Conjugate

• Unconjugated

Form

• Lyophilized

Concentration

• 1 mg/mL

Purification

• Affinity chromatography

Storage Buffer

• PBS, pH 7.3, with 8% trehalose

Contains

• No preservative

Storage Conditions

• –20°C, Avoid Freeze/Thaw Cycles

Shipping Conditions

• Ambient (domestic)
• Wet ice (international)

Product Specific Information

For reconstitution, add 100 µL distilled water to obtain a final concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (recommended: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).

Target Information

The de novo synthesis of pyrimidine nucleotides is essential for mammalian cell proliferation.
This gene encodes a trifunctional protein associated with the enzymatic activities of the first three enzymes in the six-step pathway of pyrimidine biosynthesis: carbamoylphosphate synthetase (CPS II), aspartate transcarbamoylase, and dihydroorotase.
This protein is regulated by the MAPK cascade, indicating a link between MAPK activation and de novo pyrimidine biosynthesis.

For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.