Thermo Fisher Scientific MTRR Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 50-230 of human MTRR (NP_0024452) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:MTRR,uniProtId:Q9UBK8-2,ncbiNodeId:9606,antigenRange:50-230,antigenLength:698,antigenImageFileName:PA5-89941_MTRR_Q9UBK8-2_Rabbit.svg,antigenImageFileNamePDP:PA5-89941_MTRR_Q9UBK8-2_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.71 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.01% thimerosal

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2805855

Product Specific Information

Immunogen sequence: TAPLVVVVST TGTGDPPDTA RKFVKEIQNQ TLPVDFFAHL RYGLLGLGDS EYTYFCNGGK IIDKRLQELG ARHFYDTGHA DDCVGLELVV EPWIAGLWPA LRKHFRSSRG QEEISGALPV ASPASSRTDL VKSELLHIES QVELLRFDDS GRKDSEVLKQ NAVNSNQSNV VIEDFESSLT R; Positive Samples: A-549, HeLa, LO2, 293T; Cellular Location: Cytoplasm, Cytoplasm

Target Information

Methionine is an essential amino acid required for protein synthesis and one-carbon metabolism. Its synthesis is catalyzed by the enzyme methionine synthase. Methionine synthase eventually becomes inactive due to the oxidation of its cob(I)alamin cofactor. The protein encoded by this gene regenerates a functional methionine synthase via reductive methylation. It is a member of the ferredoxin-NADP(+) reductase (FNR) family of electron transferases. Patients of the cbl-E complementation group of disorders of folate/cobalamin metabolism are defective in reductive activation of methionine synthase. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.