Thermo Fisher Scientific BCAS1 Polyclonal Antibody
BCAS1 단백질을 인식하는 Rabbit Polyclonal 항체로, Western Blot 및 IHC에 적합합니다. 합성 펩타이드(aa 5-50)를 면역원으로 제작되었으며, 사람 시료에 반응합니다. 동결건조 형태로 제공되며, 장기 보관 시 -20°C에서 안정적으로 보관 가능합니다.
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- OSB00088W-100UL
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:300–1:2,000 | - |
| Immunohistochemistry (IHC) | 1:300–1:2,000 | - |
| Miscellaneous PubMed (Misc) | - | View 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from aa region 5–50 of human BCAS1 conjugated to blue carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of sterile water.
- Centrifuge to remove any insoluble material.
- Specificity: BCAS1.
Target Information
BCAS1 was identified through positional cloning and was found to be overexpressed in most but not all breast cancer cell lines. BCAS1 is cytoplasmically localized and is thought to form homodimers through coiled-coil structures. High levels of BCAS1 mRNA are seen in brain and prostate tissues, with lower amounts observed in colon, intestine, and testis. Cells engineered to overexpress BCAS1 did not lose anchorage-dependent growth or increase their rate of growth, suggesting that BCAS1 is not a prototypical oncogene. The BCAS1 gene was also found to be amplified in other carcinomas such as pancreatic carcinoma, suggesting that BCAS1 may play an important role in the control of cell proliferation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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