Thermo Fisher Scientific TRAG3 Polyclonal Antibody
인간 TRAG3 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체. Western blot 및 ELISA에 사용 가능. 암세포주에서 TRAG3 발현 연구에 적합. Taxol 내성 관련 항원 연구용으로 설계됨.
- 카탈로그번호
- PA112868
- 판매단위
- pk
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Thermo Fisher Scientific TRAG3 Polyclonal Antibody
Applications
- Western Blot (WB): Assay-dependent
- ELISA (ELISA): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to human Trag-3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | PBS |
| Contains | 0.08% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2084765 |
Product Specific Information
This protein is expressed in various tumor cell lines including carcinomas, myeloid or lymphoid malignancies, melanomas, or prostate cancer. It is also weakly expressed in kidney and overexpressed in taxol-resistant breast cancer line MDA 435(TR) or the doxorubicin-resistant multiple myeloma lines 8226/Dox(40) or 8226/MDR(10)V.1.
Target Information
The expression of the cancer-testis antigen Taxol resistance-associated gene-3 (TRAG-3) is associated with acquired paclitaxel (Taxol) resistance and is expressed in a variety of cancers including breast cancer, leukemia, and melanoma. Overexpressed in taxol-resistant breast cancer line MDA 435(TR) and the doxorubicin-resistant multiple myeloma lines 8226/Dox(40) and 8226/MDR(10)V. Weakly expressed in kidney. TRAG-3 is an attractive target for immunotherapy of cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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