Thermo Fisher Scientific Human BFAR Synthetic Peptide
인간 BFAR 단백질의 C-말단 14 아미노산 서열에 해당하는 합성 펩타이드로, PA5-20894 항체의 블로킹 펩타이드로 사용 가능. 세포 사멸 조절 연구용으로 적합하며, 액상 형태로 제공되고 PBS 완충액에 보관. 연구용 한정 제품.
- 카탈로그번호
- PEP1008
- 카테고리
- Protein
- 판매단위
- pk
카탈로그
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
Product Specific Information
This peptide corresponds to 14 amino acids near the carboxy terminus of human BFAR.
PEP-1008 can be used as a blocking peptide with polyclonal antibody PA5-20894.
Target Information
The bifunctional apoptosis regulator (BFAR) is a scaffold protein that integrates signaling components of the cell’s apoptosis-regulatory machinery.
BFAR is a multidomain protein capable of inhibiting apoptosis induced by TNF-family death receptors (extrinsic pathway) as well as mitochondria-dependent apoptosis (intrinsic pathway).
Interaction of BFAR with Bcl-2 or Bcl-XL via a SAM domain may contribute to its anti-apoptotic properties. In addition, BFAR contains a DED-like domain that can suppress apoptosis mediated at the receptor level. BFAR is also thought to be involved in the regulation of neuronal survival.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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