Thermo Fisher Scientific HFE2 Polyclonal Antibody
HFE2 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체로, Western blot에 적합합니다. 인간, 생쥐, 랫트 시료에 반응하며 항원 친화 크로마토그래피로 정제되었습니다. 철 대사 관련 연구 및 헵시딘 경로 연구에 유용합니다.
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Applications
- Western Blot (WB): 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant full length Human HFE2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2720447 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen. The purity is greater than 95% (by SDS-PAGE).
Target Information
HFE2 is involved in iron metabolism and may participate in the signaling pathway that activates hepcidin or modulate its expression. It could act as a receptor for hepcidin. Mutations in this gene cause hemochromatosis type 2A (juvenile hemochromatosis), an early-onset autosomal recessive disorder characterized by severe iron overload leading to hypogonadotropic hypogonadism, hepatic fibrosis or cirrhosis, and cardiomyopathy, typically occurring before age 30.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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