Thermo Fisher Scientific EPHB1 Monoclonal Antibody (4G6)
인간 EPHB1 단백질을 인식하는 Mouse monoclonal antibody (clone 4G6). Western blot과 ELISA에 적합. Affinity chromatography로 정제된 액상 항체로, PBS(pH 7.4) 용액에 보존제 없이 제공. 신경 및 혈관 발달 연구에 활용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| ELISA | 0.03 ng/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 4G6 |
| Immunogen | EPHB1 (NP_004432.1, 221–320 a.a.) partial recombinant protein with GST tag (GST tag MW: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
ARGTCIPNAE EVDVPIKLYC NGDGEWMVPI GRCTCKPGYE PENSVACKAC PAGTFKASQE AEGCSHCPSN SRSPAEASPI CTCRTGYYRA DFDPPEVACT
Target Information
EPHB1 is a receptor tyrosine kinase belonging to the ephrin receptor family. Members of this family are involved in key biological processes such as nervous system development, angiogenesis, and synapse formation. EphB1 and related proteins are type I transmembrane proteins composed of immunoglobulin, fibronectin type III, and cysteine-rich domains in the ectodomain, and a cytoplasmic tyrosine kinase domain followed by a SAM domain. EphB family proteins bind ephrin-B class ligands, which are also transmembrane signaling molecules. EphB1 is mainly expressed in developing neural tissues and vascular endothelium, regulating cell adhesion and assembly upon ephrin-B1 binding. These proteins are implicated in neuronal and vascular targeting.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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