Thermo Fisher Scientific EPHB2 Monoclonal Antibody (3B3)
인간 EPHB2 단백질을 인식하는 Mouse IgG2a 단클론 항체로 Western Blot 및 ELISA에 적합. 액상 형태, PBS(pH 7.4) 저장, 보존제 없음. -20°C에서 보관하며 반복 동결/해동을 피해야 함. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1–5 µg/mL
ELISA
- Tested Dilution: 3 ng/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 3B3 |
| Immunogen | EPHB2 (NP_059145, 226–325 a.a.) partial recombinant protein with GST tag (GST tag MW: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
CIANAEEVDV PIKLYCNGDG EWLVPIGRCM CKAGFEAVEN GTVCRGCPSG TFKANQGDEA CTHCPINSRT TSEGATNCVC RNGYYRADLD PLDMPCTTIP
Target Information
EPHB2 is a receptor tyrosine kinase belonging to the ephrin receptor family. Eph family kinases are involved in nervous system development, angiogenesis, and synapse formation and maturation.
Ephrins are divided into two classes:
- Ephrin-A (EFNA): Membrane-anchored via glycosylphosphatidylinositol linkage
- Ephrin-B (EFNB): Transmembrane proteins
Eph receptors are grouped based on extracellular domain sequence similarity and ligand affinity. Ephrin receptors form the largest subgroup of the receptor tyrosine kinase (RTK) family. EphB4 binds ephrin-B2 and is essential for vascular development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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