Thermo Fisher Scientific RARS Polyclonal Antibody
Human RARS(Arginyl-tRNA Synthetase)를 인식하는 Rabbit Polyclonal Antibody. Western blot 및 Immunoprecipitation에 적합. 항원 친화 크로마토그래피로 정제된 액상 항체이며, 4°C에서 보관. 연구용 전용 제품.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunoprecipitation (IP) | 2–10 µg/mg lysate |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 1–50 of Human Arginyl-tRNA Synthetase (RARS, UniProt ID: P54136-1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Phosphate/Tris citrate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Target Information
The fidelity of protein synthesis requires efficient discrimination of amino acid substrates by aminoacyl-tRNA synthetases. ArgRS (Arginyl-tRNA synthetase), also known as RARS or DALRD1, belongs to the class-I aminoacyl-tRNA synthetase family, which includes LeuRS, ValRS, and IleRS. These proteins catalyze the aminoacylation of tRNA by their cognate amino acid. ArgRS localizes to the cytoplasm, existing as a monomer but also associates with other tRNA synthetases and auxiliary proteins to form a multisubunit complex. In the presence of ATP, arginine (Arg), and tRNA, ArgRS joins Arg to tRNA(Arg) at its synthetic active site. Two cytoplasmic forms of ArgRS have been described in mammals, differing by a 73-amino-acid sequence required for ArgRS assembly into the multisubunit complex.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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