Thermo Fisher Scientific COG2 Polyclonal Antibody
COG2 단백질을 인식하는 Rabbit Polyclonal 항체로 Western Blot에 적합합니다. Human에 반응하며 Mouse, Rat, Zebrafish, Bovine에서도 예측 반응성을 보입니다. 항원 친화 크로마토그래피로 정제되었으며, 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 1–217 of Human COG2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.45 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1M Tris glycine, pH 7, with 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2548184 |
Product Specific Information
- Recommended positive controls: Jurkat, Raji
- Predicted reactivity: Mouse (94%), Rat (93%), Zebrafish (82%), Bovine (96%)
- Store product as a concentrated solution.
- Centrifuge briefly prior to opening the vial.
Target Information
The structure and function of the Golgi apparatus is controlled by a number of multi-protein complexes involved in glycosylation reactions and vesicular transport.
The conserved oligomeric Golgi (COG) complex consists of three subcomplexes—LDLC, SEC34, and GTT (Golgi transport complex)—each containing proteins necessary for proper Golgi operation.
COG2 (conserved oligomeric Golgi complex subunit 2), also known as LDLC, is a 730-amino acid component of the COG complex. Localized to the cytoplasmic side of the Golgi apparatus, COG2 is required for proper Golgi morphology and function, specifically playing a role in Golgi ribbon formation and vesicular transport.
Abnormal COG2 function may cause cell death, suggesting that COG2 is an important factor in cell viability.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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