Thermo Fisher Scientific ZBTB8A Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 200-400 of human ZBTB8A (NP_001035531) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:ZBTB8A,uniProtId:Q96BR9-1,ncbiNodeId:9606,antigenRange:200-400,antigenLength:441,antigenImageFileName:PA5-116783_ZBTB8A_Q96BR9-1_Rabbit.svg,antigenImageFileNamePDP:PA5-116783_ZBTB8A_Q96BR9-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.82 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.01% thimerosal

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2901414

Product Specific Information

Positive Samples: U-87MG, PC-3, HeLa, Mouse lung, Mouse brain, Rat heart

Immunogen sequence: HEPRKESIKK TKHLRLSQPS EVTHYKSSKR EVRTSDSSSH VSQSEEQAQI DAEMDSTPVG YQYGQGSDVT SKSFPDDLPR MRFKCPYCTH VVKRKADLKR HLRCHTGERP YPCQACGKRF SRLDHLSSHF RTIHQACKLI CRKCKRHVTD LTGQVVQEGT RRYRLCNECL AEFGIDSLPI DLEAEQHLMS PSDGDKDSRW H

Target Information

The ZBTB family of proteins is comprised of diverse zinc finger proteins that also contain a BTB (BR-C, ttk and bab) domain. ZBTB8, also known as BOZ-F1, is present in multiple tissues, and is highly expressed in the cytoplasm of the placenta. While little is known about ZBTB8, other ZBTB proteins, such as ZBTB4 bind methylated DNA and repress transcription. Another ZBTB proteins, ZBTB7A, has been implicated as a proto-oncogene whose overexpression contributes to malignancy in breast cancer, suggesting that ZBTB8 may act as a transcriptional repressor or be involved in tumorigenesis.

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.