Thermo Fisher Scientific HDAC2 Polyclonal Antibody, Alexa Fluor 488

Thermo Fisher Scientific HDAC2 Polyclonal Antibody, Alexa Fluor 488

Applications

• Immunocytochemistry (ICC/IF)

Tested Dilution: 1–10 µg/mL
Publications: -

Product Specifications

Product Specific Information

PA1861A488 detects histone deacetylase 2 (HDAC2) from canine, hamster, human, mouse, non-human primate, and rat tissues and cells.
The immunogen is a synthetic peptide corresponding to residues C T(475) D T K G T K S E Q L S N P(488) of human HDAC2.
This immunizing peptide (Cat. # PEP-070) is available for use in neutralization and control experiments.

Target Information

HDAC2 belongs to the histone deacetylase family. These enzymes form large multiprotein complexes and deacetylate lysine residues at the N-terminal regions of core histones (H2A, H2B, H3, and H4).
HDAC2 forms transcriptional repressor complexes with various proteins, including YY1, a zinc-finger transcription factor.
It plays an important role in transcriptional regulation, cell cycle progression, and developmental processes.
Alternative splicing results in multiple transcript variants.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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