Thermo Fisher Scientific PCGF3 Polyclonal Antibody, MaxPab

Applications

• Western Blot (WB): 1:500–1:1,000
• Immunocytochemistry (ICC/IF): 10 µg/mL

Product Specifications

Product Specific Information

Sequence of this protein is as follows:
MLTRKIKLWD INAHITCRLC SGYLIDATTV TECLHTFCRS CLVKYLEENN TCPTCRIVIH QSHPLQYIGH DRTMQDIVYK LVPGLQEAEM RKQREFYHKL GMEVPGDIKG ETCSAKQHLD SHRNGETKAD DSSNKEAAEE KPEEDNDYHR SDEQVSICLE CNSSKLRGLK RKWIRCSAQA TVLHLKKFIA KKLNLSSFNE LDILCNEEIL GKDHTLKFVV VTRWRFKKAP LLLHYRPKMD LL

Target Information

Phosphorylase kinase is a hexadecameric enzyme composed of four copies of four subunits encoded by separate genes: PHKA, PHKB, PHKG, and PH kDa.
This serine/threonine-specific kinase converts glycogen phosphorylase b to glycogen phosphorylase a, releasing glucose-1-phosphate from glycogen.
PHKB (Phosphorylase b kinase regulatory subunit beta) is a 1093 amino acid subunit with regulatory functions controlled by phosphorylation.
Defects in the PHKB gene cause glycogen storage disease type 9B, characterized by mild hepatomegaly, slightly elevated transaminase and plasma lipids, no muscle involvement, and gradual improvement with age.
Four isoforms of PHKB are produced by alternative splicing.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.