Thermo Fisher Scientific Human IgG1 Monoclonal Antibody (HP6069)
Human IgG1을 표적으로 하는 마우스 단클론 항체로, WB, IHC, Flow, ELISA 등 다양한 실험에 사용 가능. Protein A로 정제된 액상 형태이며, 안정적 저장 및 높은 특이성 제공. 연구용으로만 사용.
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Thermo Fisher Scientific Human IgG1 Monoclonal Antibody (HP6069)
Applications 및 Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1–1 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 2–10 µg/mL |
| Flow Cytometry (Flow) | Assay-dependent |
| ELISA | 0.01–0.1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | HP6069 |
| Immunogen | Human immunoglobulin IgG1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS with proprietary stabilizer |
| Contains | 0.01% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Positive control: plasma
- Cellular location: Secreted
Target Information
This antibody recognizes the constant region of immunoglobulin heavy chains.
Immunoglobulins (antibodies) are membrane-bound or secreted glycoproteins produced by B lymphocytes.
In the recognition phase of humoral immunity, membrane-bound immunoglobulins act as receptors that trigger clonal expansion and differentiation of B lymphocytes into plasma cells upon antigen binding.
Secreted immunoglobulins mediate the effector phase of humoral immunity, eliminating bound antigens (PubMed:22158414, PubMed:20176268).
Each immunoglobulin has two antigen-binding sites formed by variable domains of heavy and light chains.
The variable domains are assembled by V-(D)-J rearrangement and undergo somatic hypermutation for affinity maturation (PubMed:17576170, PubMed:20176268).
[UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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