Thermo Fisher Scientific Human IgG4 Monoclonal Antibody (HP6025)
Human IgG4 특이적 단클론 항체로, Western blot, IHC, Flow cytometry, ELISA 등 다양한 면역 분석에 적합. Mouse IgG1 아이소타입으로 단백질 A 정제, 액상 형태. 인체 IgG4 연구 및 면역 반응 분석에 활용 가능.
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Thermo Fisher Scientific Human IgG4 Monoclonal Antibody (HP6025)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1–1 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 2–10 µg/mL |
| Flow Cytometry (Flow) | Assay-dependent |
| ELISA | 0.01–0.1 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | HP6025 |
| Immunogen | Human immunoglobulin IgG4 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS with proprietary stabilizer |
| Contains | 0.01% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Positive control: Plasma
- Cellular location: Secreted
Target Information
Human IgG4, also known as human immunoglobulin G4, is a subclass of human IgG antibodies produced by the immune system in response to antigens. It is the least abundant IgG subclass in the blood and plays a minor role in pathogen defense. IgG4 binds specific antigens and promotes their clearance through mechanisms such as phagocytosis and complement activation. It is also involved in immune tolerance and inflammation suppression.
Human IgG4 is useful for studying immune responses and developing diagnostic or therapeutic tools for infectious and autoimmune diseases.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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