Thermo Fisher Scientific SARS-CoV-2 Spike Protein (RBD) Polyclonal Antibody
SARS-CoV-2 스파이크 단백질(RBD)에 특이적인 토끼 폴리클로날 항체로, WB, ICC/IF, ELISA, IP 등 다양한 응용에 사용 가능. 고순도 친화 크로마토그래피 정제 및 0.93 mg/mL 농도의 액상 형태. 바이러스 연구 및 SARS-CoV-2 관련 단백질 분석에 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:50,000–1:200,000 |
| Immunoprecipitation (IP) | 0.5 µg–4 µg antibody for 200 µg–400 µg extracts |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Virus |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 332–550 of coronavirus Spike RBD (YP_0097243901) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.93 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2901545 |
Product Specific Information
- Positive Samples: 293T
- Immunogen Sequence:
ITNLCPFGEV FNATRFASVY AWNRKRISNC VADYSVLYNS ASFSTFKCYG VSPTKLNDLC FTNVYADSFV IRGDEVRQIA PGQTGKIADY NYKLPDDFTG CVIAWNSNNL DSKVGGNYNY LYRLFRKSNL KPFERDISTE IYQAGSTPCN GVEGFNCYFP LQSYGFQPTN GVGYQPYRVV VLSFELLHAP ATVCGPKKST NLVKNKCVNF NFNGLTGTG
Target Information
SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2), also known as 2019-nCoV, is responsible for illnesses ranging from mild cold-like symptoms to severe respiratory distress and death. The Spike (S) protein mediates viral attachment, fusion, and entry, making it a key target for antibody and vaccine development.
The receptor-binding domain (RBD, S-RBD) of the Spike protein binds strongly to human and bat ACE2 receptors, exhibiting higher affinity than SARS-CoV RBD. The S1 subunit contains the RBD responsible for ACE2 binding on target cells.
⚠ WARNING: This product can expose you to chemicals including mercury, known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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