Thermo Fisher Scientific IKZF3 Monoclonal Antibody (OTI1E1), TrueMAB
IKZF3 단백질을 인식하는 마우스 단일클론 항체로, 인간 시료에 반응. WB에 1:2,000 희석 비율로 검증됨. 동결건조 형태로 제공되며, -20°C에서 보관. B 림프구 발달 및 전사 조절 연구에 적합.
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Applications
- Western Blot (WB): Tested at 1:2,000 dilution
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1E1 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–301 of human IKZF3 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL (Product #89882).
Target Information
This gene encodes a member of the Ikaros family of zinc-finger proteins. Members such as Ikaros, Aiolos, and Helios are hematopoietic-specific transcription factors that regulate lymphocyte development.
Aiolos (IKZF3) plays a critical role in B lymphocyte proliferation and differentiation, participating in chromatin remodeling and forming various homo- and heterodimers with Ikaros.
At least six alternative transcripts encoding different isoforms have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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