Thermo Fisher Scientific PSMD5/26S Proteasome Subunit S5B Polyclonal Antibody
Rabbit polyclonal antibody targeting human PSMD5 (26S Proteasome Subunit S5B). Validated for WB and IP applications. Supplied as liquid, unconjugated form at 1 mg/mL concentration. Recommended storage at 4°C and 1-year shelf life.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: 2–10 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 325–375 of Human 26S proteasome non-ATPase regulatory subunit 5 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Target Information
The 26S proteasome is a multicatalytic proteinase complex composed of two major subcomplexes: a 20S core and a 19S regulator.
- The 20S core consists of four rings of 28 non-identical subunits (two alpha and two beta rings).
- The 19S regulator includes a base (6 ATPase and 2 non-ATPase subunits) and a lid (up to 10 non-ATPase subunits).
Proteasomes are abundant in eukaryotic cells and degrade peptides via an ATP/ubiquitin-dependent, non-lysosomal pathway.
The immunoproteasome variant plays an essential role in processing class I MHC peptides.
This gene encodes a non-ATPase subunit of the 19S regulator base.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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