Thermo Fisher Scientific PSMD5/26S Proteasome Subunit S5B Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:2,000–1:10,000

Immunoprecipitation (IP)

• Tested Dilution: 2–10 µg/mg lysate

Product Specifications

Product Specific Information

The recommended shelf life for this product is 1 year from date of receipt.

Target Information

The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of two complexes: a 20S core and a 19S regulator.

• The 20S core consists of four rings of 28 non-identical subunits (two rings of seven alpha subunits and two rings of seven beta subunits).
• The 19S regulator includes a base (containing six ATPase subunits and two non-ATPase subunits) and a lid (containing up to ten non-ATPase subunits).
  Proteasomes are widely distributed in eukaryotic cells and cleave peptides in an ATP/ubiquitin-dependent, non-lysosomal pathway.
  The immunoproteasome plays a key role in processing class I MHC peptides.
  This gene encodes a non-ATPase subunit of the 19S regulator base.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.