Thermo Fisher Scientific SAFB1 Polyclonal Antibody
Thermo Fisher Scientific의 SAFB1 Polyclonal Antibody는 인간 SAFB 단백질을 인식하는 Rabbit IgG 항체로, WB, IHC, IP 등 다양한 응용에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 액상 형태로 제공되어 높은 특이성과 안정성을 보장합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunohistochemistry (IHC) | 1:100–1:500 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:100–1:500 |
| Immunoprecipitation (IP) | 2–5 µg/mg lysate |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 775 and 825 of Human Scaffold Attachment Factor B (SAFB, UniProt ID: Q15424-1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | TBS, pH 7.0–8.0, with 0.1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- For IHC: Epitope retrieval with citrate buffer (pH 6.0) is recommended for FFPE tissue sections
- Based on 100% sequence identity, this antibody is predicted to react with Orangutan
Target Information
This gene encodes a DNA-binding protein with high specificity for scaffold or matrix attachment region (S/MAR) DNA elements. It is involved in attaching chromatin loops to the nuclear matrix and may serve as a molecular base to assemble a transcriptosome complex near actively transcribed genes. The protein regulates heat shock protein 27 transcription, acts as an estrogen receptor co-repressor, and is a candidate for breast tumorigenesis. Multiple transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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