Thermo Fisher Scientific LYL1 Polyclonal Antibody
LYL1 단백질을 인식하는 Rabbit Polyclonal Antibody로, ICC/IF 실험에 적합. 인간 시료에 반응하며 항원 친화 크로마토그래피로 정제됨. PBS 기반 용액 형태로 제공되며, 장기 보관 시 -20°C에서 안정적. 연구용으로만 사용 가능.
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human LYL1. Recombinant protein control fragment (Product #RP-108028) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2662558 |
Product Specific Information
- Immunogen sequence: CPPQAQAEVGP TMTEKAEMVC A
- Highest antigen sequence identity to the following orthologs: mouse 82%, rat 82%
Target Information
Lyl-1, TAL1, and TAL2 are part of a family of basic helix-loop-helix (bHLH) proteins implicated in T cell acute leukemia.
TAL1 (SCL) is a serine phosphoprotein and transcription factor regulating embryonic hematopoiesis.
TAL2 is involved in T cell acute lymphoblastic leukemia through a chromosomal translocation with T cell receptor β chain genes.
Lyl-1 (lymphoblastic leukemia-derived sequence 1) is a nuclear protein forming heterodimeric complexes with E2α proteins, exhibiting distinctive DNA-binding properties in hematolymphoid cells.
Lyl-1 is associated with chromosomal aberrations causing a form of T cell acute lymphoblastic leukemia (T-ALL).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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