Thermo Fisher Scientific GALNT9 Polyclonal Antibody

Applications

• Immunocytochemistry (ICC/IF): 0.25–2 µg/mL

Product Specifications

Product Specific Information

Immunogen sequence:
RVYNNTLTYGE VRNSKASAYC LDQGAEDGDR AILYPCHGMS SQLVRYSADG LLQL

Highest antigen sequence identity to the following orthologs:

• Mouse: 93%
• Rat: 95%

Target Information

This gene encodes a member of the UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAc-T) family of enzymes.
GalNAc-Ts initiate mucin-type O-linked glycosylation in the Golgi apparatus by catalyzing the transfer of GalNAc to serine and threonine residues on target proteins. They are characterized by:

• An N-terminal transmembrane domain
• A stem region
• A lumenal catalytic domain containing a GT1 motif and Gal/GalNAc transferase motif
• A C-terminal ricin/lectin-like domain

GalNAc-Ts have different but overlapping substrate specificities and expression patterns. This gene is expressed specifically in the brain, with highest expression in the cerebellum. Multiple transcript variants encoding different isoforms have been identified.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.