Thermo Fisher Scientific ZFP36 Monoclonal Antibody (OTI8B5), TrueMAB
ZFP36 단백질을 인식하는 마우스 단클론 항체로, Western blot, IHC, ICC/IF, Flow Cytometry에 적합합니다. 인간 시료 반응성, 액상 형태, 고순도 친화 크로마토그래피 정제 제품입니다. 연구용으로만 사용 가능합니다.
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Thermo Fisher Scientific ZFP36 Monoclonal Antibody (OTI8B5), TrueMAB
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| Item | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI8B5 |
| Immunogen | Full length human recombinant protein of human ZFP36 produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
ZFP36 is a probable regulatory protein with a novel zinc finger structure involved in regulating the response to growth factors. Knockdown of ZFP36 increases macrophage gene mRNAs and inflammatory tumor necrosis factor release, while overexpression decreases those levels, supporting its role in macrophage gene regulation. ZFP36 contains multiple phosphorylation sites and can be phosphorylated by JNK and other MAP kinases. Gene expression profiling links ZFP36 to prostate cancer outcomes, and dysregulation may contribute to rheumatoid arthritis activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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