Thermo Fisher Scientific LC3B Polyclonal Antibody
LC3B 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western Blot 및 IHC(Paraffin) 실험에 적합합니다. 인간 시료에 반응하며, 오토파지 관련 연구용으로 사용됩니다. Protein A 및 항원 친화 크로마토그래피로 정제된 액상 형태 제품입니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide between 23–52 amino acids from human LC3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2900908 |
Target Information
LC3B (Autophagy Marker Light Chain 3B, MAP1A/MAP1B LC3 B) in humans is encoded by the gene MAP1LC3B (Microtubule-associated proteins 1A/1B light chain 3B).
LC3B is associated with microtubule assembly and plays an important role in neurogenesis and autophagy — a process involving bulk degradation of cytoplasmic components.
Three human LC3 isoforms undergo post-translational modifications during autophagy. Macroautophagy is the major inducible pathway for cytoplasmic turnover, responsible for degradation of enzymes and organelles during nutrient starvation.
LC3B mediates interactions between microtubules and cytoskeleton components and may be involved in cancer, aging, metabolic, neurodegenerative, and cardiovascular/pulmonary diseases.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일명: PA5-116274_LC3B_Q9GZQ8-1_Rabbit_PDP.jpeg, PA5-116274_LC3B_A6NCE7-1_Rabbit_PDP.jpeg)
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