Thermo Fisher Scientific CD13 Polyclonal Antibody
CD13 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB, IHC, ICC, Flow Cytometry에 사용 가능. 인간 및 생쥐 반응성. 고순도 항원 친화 크로마토그래피 정제. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:20,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:400 |
| Flow Cytometry (Flow) | 1:50–1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein within Human CD13 (aa 273–448) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol, 0.2% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | –20°C, Avoid Freeze/Thaw Cycles, store in dark |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2854725 |
Product Specific Information
Positive Control: Rat kidney tissue, HT-29, A549, human liver tissue, human prostate cancer tissue, human kidney tissue, mouse colon tissue.
Target Information
CD13 (ANPEP) is a 150–170 kDa type II transmembrane zinc-binding ectopeptidase expressed on various cell types. It is a metalloprotease that removes neutral amino acids from small peptides, activating or inactivating bioactive peptides. CD13 is involved in extracellular matrix degradation, antigen processing, and signal transduction. It plays a role in inflammatory responses, intercellular contact regulation, cell motility, and vascularization. CD13 is expressed by granulocytes, monocytes, and myeloid leukemia cells, and its expression is associated with poor carcinoma prognosis. CD13 functions as an aminopeptidase enzyme and also serves as an alpha receptor for coronavirus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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