Thermo Fisher Scientific Cdc25C Monoclonal Antibody (1F12)
Human CDC25C 단백질을 인식하는 Mouse IgG1 단클론 항체로, WB, IHC, ELISA에 적합합니다. 약 58kDa 단백질 검출에 사용되며, 세포 분열 조절 연구에 유용합니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:1,000 |
| ELISA | 1:10,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1F12 |
| Immunogen | Purified recombinant fragment of human CDC25C expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not determined |
| Storage Buffer | Ascites |
| Contains | 0.03% sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_10990166 |
Product Specific Information
MA5-15613 targets CDC25C in indirect ELISA, IHC, and WB applications, showing reactivity with human samples.
The immunogen is a purified recombinant fragment of human CDC25C expressed in E. coli.
MA5-15613 detects CDC25C, which has a predicted molecular weight of approximately 58 kDa.
Target Information
M-phase inducer phosphatase 3 is an enzyme encoded by the CDC25C gene in humans. This gene is highly conserved during evolution and plays a key role in regulating cell division.
The encoded protein is a tyrosine phosphatase belonging to the Cdc25 phosphatase family, directing dephosphorylation of cyclin B-bound CDC2 (CDK1) and triggering entry into mitosis.
It is also thought to suppress p53-induced growth arrest. Multiple alternatively spliced transcript variants have been described, though the full-length nature of many is not known.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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