Thermo Fisher Scientific ENPP2 Polyclonal Antibody
Human ENPP2 단백질을 인식하는 Rabbit Polyclonal 항체로, ICC/IF에 0.25–2 µg/mL 농도로 사용 가능. 항원 친화 크로마토그래피로 정제되었으며 PBS/glycerol buffer에 보관. 암세포 이동 및 혈관신생 관련 연구에 적합.
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Applications
Immunocytochemistry (ICC/IF)
- Tested dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human ENPP2. Recombinant protein control fragment (Product #RP-106483) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C (short term). For long-term storage, store at -20°C. Avoid freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2663265 |
Product Specific Information
Immunogen sequence:
TNPLREIDKIV GQLMDGLKQL KLHRCVNVIF VGDHGMEDVT CDRTEFLSNY LTNVDDITLV PGTLGRIRSK FSNNAKYDPK AIIANLT
- Highest antigen sequence identity to orthologs: mouse 94%, rat 92%
Target Information
The protein encoded by this gene functions as both a phosphodiesterase (cleaving phosphodiester bonds at the 5′ end of oligonucleotides) and a phospholipase (catalyzing production of lysophosphatidic acid, LPA, in extracellular fluids).
LPA evokes growth factor-like responses including stimulation of cell proliferation and chemotaxis.
This gene product stimulates tumor cell motility and has angiogenic properties. Its expression is upregulated in various carcinomas. The gene product is secreted and further processed to form the biologically active protein.
Several alternatively spliced transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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