Thermo Fisher Scientific GNAO1 Polyclonal Antibody
GNAO1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB 및 Flow Cytometry에 적합합니다. Human, Mouse, Rat 반응성이 있으며, KLH 결합 합성 펩타이드로 면역화되었습니다. Protein A 및 항원 친화 크로마토그래피로 정제되어 높은 특이성과 안정성을 제공합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Flow Cytometry (Flow)
- Tested Dilution: 1:10–1:50
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide between 291–320 amino acids from the C-terminal region of human GNAO1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.25 mg/mL |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2543642 |
Product Specific Information
This antibody is predicted to react with bovine based on sequence homology.
Target Information
Heterotrimeric G proteins are membrane-bound GTPases linked to 7-TM receptors. Each G protein contains alpha-, beta-, and gamma-subunits and is bound to GDP in the "off" state. Ligand-receptor binding results in detachment of the G protein, switching it to an "on" state and permitting Galpha activation of second messenger signaling cascades. Galphas and Galphai bind directly to adenylyl cyclase to stimulate or inhibit its activity, leading to an increase or decrease in cAMP levels, respectively.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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