Thermo Fisher Scientific C1QA/Complement C1q A-Chain Monoclonal Antibody (C1QA/2953)
인간 C1QA 단백질을 인식하는 Mouse monoclonal 항체로 Western blot, IHC 등 다양한 응용에 적합합니다. Protein A/G로 정제된 액상 형태이며, 4°C에서 보관합니다. 보체 경로 연구 및 루푸스 관련 연구에 유용합니다.
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Applications and Tested Dilution
| Application | Tested Dilution | Notes |
|---|---|---|
| Western Blot (WB) | 1–2 µg/mL | |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent | |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL | |
| Peptide Array (Array) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | C1QA/2953 |
| Immunogen | Recombinant fragment (around aa 104–237) of human C1QA protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
C1q is a sub-component of complement C1, which associates with complement components C1r and C1s required for the proteolytic complement cascade. Deficiency of C1q has been linked to lupus erythematosus and glomerulonephritis. C1q is composed of 18 polypeptide chains: six A-chains, six B-chains, and six C-chains. Each chain contains a collagen-like region near the N-terminus and a C-terminal globular region. The A-, B-, and C-chains are arranged in the order A–C–B on chromosome 1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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