Thermo Fisher Scientific H1FOO Polyclonal Antibody
Human H1FOO 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 IHC(P)에서 검증됨. 항원 친화 크로마토그래피로 정제되었으며, PBS와 40% glycerol 용액 형태로 제공. 단기 4°C, 장기 -20°C 보관 권장.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human H1FOO. Recombinant protein control fragment (Product #RP-96499) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.10 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2642288 |
Product Specific Information
Immunogen sequence:
YRKTKAESKS SKPTASKVKN GAASPTKKKV VAKAKAPKAG QGPNTKAAAP AKGSGSKVVP AHLSRKTEAP KGPRKAGLPI KASSSKVSSQ
Highest antigen sequence identity to the following orthologs:
- Mouse: 33%
- Rat: 36%
Target Information
Eukaryotic Histones are basic and water-soluble nuclear proteins that form hetero-octameric nucleosome particles by wrapping 146 base pairs of DNA in a left-handed super-helical turn to form chromosomal fibers.
Two molecules each of the four core Histones (H2A, H2B, H3, and H4) form the octamer, consisting of two H2A-H2B dimers and two H3-H4 dimers.
Over 80% of nucleosomes contain the linker Histone H1, which interacts with linker DNA between nucleosomes and mediates higher-order chromatin compaction.
H1FOO (H1 histone family, member O, oocyte-specific), also known as OSH1, is a 346 amino acid oocyte-specific Histone localized in both nucleus and cytoplasm. It is expressed as multiple alternatively spliced isoforms and plays an important role in gene control during oogenesis and early embryogenesis, crucial for meiotic maturation of germinal vesicle-stage oocytes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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