Thermo Fisher Scientific AGBL4 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human AGBL4. Recombinant protein control fragment (Product #RP-94511). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:AGBL4,uniProtId:Q5VU57-1,ncbiNodeId:9606,antigenRange:53-132,antigenLength:503,antigenImageFileName:PA5-58201_AGBL4_Q5VU57-1_Rabbit.svg,antigenImageFileNamePDP:PA5-58201_AGBL4_Q5VU57-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2637755

Product Specific Information

Immunogen sequence: GNLGRVDQVS EFEYDLFIRP DTCNPRFRVW FNFTVENVKE SQRVIFNIVN FSKTKSLYRD GMAPMVKSTS RPKWQRLPPK

Highest antigen sequence identity to the following orthologs: Mouse - 96%, Rat - 38%.

Target Information

Metallocarboxypeptidase that mediates deglutamylation of target proteins. Catalyzes the deglutamylation of polyglutamate side chains generated by post-translational polyglutamylation in proteins such as tubulins. Also removes polyglutamates from the carboxy-terminus of target proteins such as MYLK. Mediates deglutamylation of CGAS, regulating the antiviral activity of CGAS. Acts as a long-chain deglutamylase and specifically shortens long polyglutamate chains, while it is not able to remove the branching point glutamate, a process catalyzed by AGBL5/CCP5. [UniProt]

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.