Thermo Fisher Scientific CD61 (Integrin beta 3) Monoclonal Antibody (JM2E5), FITC
FITC 형광 표지된 CD61 (Integrin beta 3) 단클론 항체로 돼지 세포 표면 항원 인식. 유세포 분석(Flow Cytometry)에 적합하며, 단백질 A 정제 및 안정적 PBS/BSA 저장용액 제공. 혈소판 관련 연구에 활용 가능.
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Applications
- Flow Cytometry (Flow): Tested Dilution Neat-1:10
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Pig |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | JM2E5 |
| Immunogen | Porcine peripheral blood mononuclear cells |
| Conjugate | FITC |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS with 1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Store in the dark. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2745377 |
Additional Formats
- Unconjugated: MA5-28416
- Request custom conjugation: Custom Form
Product Specific Information
This antibody recognizes the porcine CD61 cell surface antigen, also known as platelet glycoprotein IIIa. CD61 is present on the megakaryocyte/platelet lineage, granulocytes, cells from the monocyte/macrophage lineage and endothelial cells.
Target Information
CD61 (GPIIIa, ITGB3) is a glycoprotein found on megakaryocytes, platelets and their precursors. It plays a role in platelet aggregation and acts as a receptor for fibrinogen, fibronectin, von Willebrand factor, and vitronectin.
CD61 associates with either alpha IIb integrin (CD41) or alpha V integrin (CD51) at the cell surface. It is expressed on platelets, megakaryocytes, endothelial cells, monocytes, and osteoclasts.
Like other integrins, CD61 participates in cell adhesion and cell-surface mediated signaling.
Diseases associated with CD61 dysfunction include Glanzmann Thrombasthenia and Platelet type-16 Bleeding Disorder.
For Research Use Only. Not for use in diagnostic procedures or resale without express authorization.
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