Thermo Fisher Scientific Ku80 Polyclonal Antibody
Ku80 단백질을 인식하는 Rabbit Polyclonal 항체로 Western blot 및 IHC(P)에서 사용 가능. 고순도(>95%)로 정제되어 신뢰성 높은 결과 제공. 인간 단백질과 반응하며 DNA 손상 복구 연구에 적합. 장기 보관 시 -20°C 권장.
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- PA586493
- 판매단위
- pk
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 450–480 of Human XRCC5 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2803270 |
Product Specific Information
Purity is >95% by SDS-PAGE.
Target Information
The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein, also known as ATP-dependent DNA helicase II or DNA repair protein XRCC5.
Ku is the DNA-binding component of the DNA-dependent protein kinase and functions with the DNA ligase IV–XRCC4 complex in the repair of DNA double-strand breaks by non-homologous end joining and in V(D)J recombination.
This gene complements Chinese hamster xrs-6 mutant cells that are defective in DNA double-strand break repair and V(D)J recombination.
A rare microsatellite polymorphism in this gene is associated with cancer in patients with varying radiosensitivity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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