Thermo Fisher Scientific KAP3 Polyclonal Antibody
KAP3 단백질을 인식하는 Rabbit Polyclonal Antibody로, 인간·마우스·랫트 반응성. WB, IHC, ICC 등 다양한 응용에 적합. 고순도 Affinity chromatography 정제 및 안정적 액상 형태로 제공. 연구용으로만 사용 가능.
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Thermo Fisher Scientific KAP3 Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human KIFAP3 (Accession Q92845), corresponding to amino acid residues Y94–E144 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2852424 |
Product Specific Information
Antibody detects endogenous levels of total KIFAP3.
Target Information
The small G protein GDP dissociation stimulator (smg GDS) is a regulator protein acting on small G proteins including Rho, Rap1, and Ki-Ras. It stimulates GDP/GTP exchange and inhibits membrane interactions.
The encoded protein contains 9 Armadillo repeats and interacts with smg GDS through these repeats. It is concentrated around the endoplasmic reticulum and phosphorylated by v-src, reducing its affinity for smg GDS.
This protein may serve as a linker between human chromosome-associated polypeptide (HCAP) and KIF3A/B, a kinesin superfamily protein in the nucleus, playing a role in chromosome–ATPase motor interactions.
Several transcript variants encoding different isoforms have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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