Thermo Fisher Scientific Angiopoietin 4 Polyclonal Antibody
인간 Angiopoietin 4 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB 및 IHC(P) 실험에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:200–1:1,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:100–1:300
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to internal residues of human angiopoietin 4 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.4 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS (pH 7.4) with 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2636053 |
Product Specific Information
This antibody detects endogenous levels of total Angiopoietin 4 protein.
Target Information
Angiopoietin-1 (Ang-1) is a secreted ligand for Tie-2, a receptor tyrosine kinase expressed in endothelial and hemopoietic cells. Ang-1 mediates blood vessel maturation and endothelial development.
Angiopoietin-2 (Ang-2) acts as a natural antagonist of Ang-1 activation of Tie-2, with expression restricted to sites of vascular remodeling.
Ang-3 and Ang-4 are mouse and human counterparts from the same gene locus, exhibiting divergent functions and distributions. Ang-3 acts as an antagonist, while Ang-4 functions as an agonist. Both share structural characteristics of Ang-1 and Ang-2, including the signal peptide, N-terminal region, coiled-coil segment, and fibrinogen-like domain.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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