Thermo Fisher Scientific ADAMTS17 Polyclonal Antibody
ADAMTS17 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체. Western blot 및 IHC(P)에서 검증됨. 인간 및 마우스 시료에 반응. 항원 친화 크로마토그래피로 정제된 고품질 항체로 연구용에 적합.
- 카탈로그번호
- PA550599
- 판매단위
- pk
카탈로그
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Applications and Tested Dilution
- Western Blot (WB): 1:500–1:2,000
- Immunohistochemistry (Paraffin) (IHC (P)): 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to internal residues of human ADAM metallopeptidase with thrombospondin type 1 motif, 17 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2.6 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2636052 |
Product Specific Information
This antibody detects endogenous levels of total ADAMTS17 protein.
Target Information
The ADAMTS17 gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) family. Members of this family share several conserved domains, including a propeptide region, metalloproteinase domain, disintegrin-like domain, and thrombospondin type 1 (TS) motif.
Individual members differ in the number of C-terminal TS motifs and may contain unique C-terminal domains.
The encoded preproprotein is proteolytically processed to form the mature protein, which may promote breast cancer cell growth and survival.
Mutations in this gene are associated with Weill-Marchesani-like syndrome, characterized by lenticular myopia, ectopia lentis, glaucoma, spherophakia, and short stature.
(Information provided by RefSeq, May 2016.)
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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