Thermo Fisher Scientific GBP5 Monoclonal Antibody (OTI3G1), TrueMAB
인간 GBP5 단백질을 인식하는 Mouse IgG1 단클론 항체로 Western Blot과 유세포분석에 적합. 동결건조 형태로 제공되며, PBS buffer에 trehalose 포함. 연구용으로만 사용 가능하며 항원은 HEK293T에서 생산된 인간 GBP5 full-length 단백질.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Flow Cytometry (Flow)
- Tested Dilution: 1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3G1 |
| Immunogen | Full length human recombinant protein of human GBP5 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
Guanylate-binding proteins (GBPs) are interferon-induced GTP-binding proteins involved in innate immunity against microbial and viral pathogens.
Humans express seven GBPs (hGBP1–hGBP7).
GBP1 and GBP2 exhibit antiviral activity and regulate endothelial cell proliferation and invasion in response to interferon (IFN).
GBP5 promotes selective NALP3 inflammasome responses to pathogenic bacteria and soluble, but not crystalline, inflammasome priming agents.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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