Thermo Fisher Scientific PKC mu Polyclonal Antibody
PKC mu 단백질을 인식하는 Rabbit Polyclonal 항체로, Human 시료에 반응합니다. ICC/IF 및 ELISA에 사용 가능하며, Protein G로 정제된 액상 형태입니다. PBS/glycerol buffer에 보관하며, 연구용으로만 사용됩니다.
- 카탈로그번호
- PA5144355
- 판매단위
- pk
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Applications
| Application | Tested Dilution |
|---|---|
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human Serine/threonine-protein kinase D1 protein (674–904 AA) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2.78 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.03% Proclin 300 |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Wet ice |
| RRID | AB_3094110 |
Target Information
The PKC family of serine/threonine kinases, including PRKCN (PKD3), is activated intracellularly by signal transduction pathways. In humans, at least 12 different PKC polypeptides have been identified. These isoforms differ in primary structure, tissue distribution, subcellular localization, mode of action in vitro, response to extracellular signals, and substrate specificity. PKC alpha, beta I, beta II, and gamma form the conventional family; their activities are Ca²⁺- and phospholipid-dependent. PKC mu activation is dependent on the phosphorylation of two activation loop sites, Ser744 and Ser748, via a PKC-dependent signaling pathway.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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