
Thermo Fisher Scientific STOML2 Monoclonal Antibody (OTI1G6), TrueMAB
STOML2 단백질을 인식하는 Mouse Monoclonal Antibody로, Western Blot 및 IHC(Paraffin)에 사용 가능. 인간 시료 반응성, 고순도 친화 크로마토그래피 정제, 1 mg/mL 농도의 액상 제품. 미토콘드리아 기능 및 세포 생리 연구에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1G6 |
| Immunogen | Full length human recombinant protein of human STOML2 produced in E.coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Target Information
Mitochondrial protein that probably regulates the biogenesis and activity of mitochondria. It stimulates cardiolipin biosynthesis and binds cardiolipin-enriched membranes where it recruits and stabilizes certain proteins, including prohibitin. This may contribute to the organization of functional microdomains in mitochondrial membranes.
Through regulation of mitochondrial function, STOML2 may be involved in various biological processes including:
- Cell migration and proliferation
- T-cell activation
- Calcium homeostasis
- Cellular response to stress
It is required for mitochondrial hyperfusion, a pro-survival cellular response to stress leading to increased ATP production. STOML2 may also regulate functional domains at the plasma membrane and play a role in T-cell activation through association with the T-cell receptor signaling complex.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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