Thermo Fisher Scientific NKG2A Polyclonal Antibody
Thermo Fisher Scientific의 NKG2A Polyclonal Antibody는 인간 NKG2A 단백질을 인식하는 토끼 유래 IgG 항체입니다. Western blot, IHC, ICC, Flow cytometry 등에 사용 가능하며, 고순도의 Protein A 및 항원 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:100 |
| Immunocytochemistry (ICC/IF) | 1:25 |
| Flow Cytometry (Flow) | 1:25 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide corresponding to amino acids 180–206 of the C-terminal region of human KLRC1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.4 mg/mL |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C (short term). For long-term storage, store at -20°C. Avoid freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2718397 |
Target Information
Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They also regulate humoral and cell-mediated immunity.
The protein encoded by this gene belongs to the killer cell lectin-like receptor (NKG2) family, a group of transmembrane proteins preferentially expressed in NK cells. These proteins have a type II membrane orientation and a C-type lectin domain.
NKG2A forms a complex with KLRD1/CD94 and recognizes MHC class I HLA-E molecules in NK cells. The NKG2 gene family is clustered on chromosome 12, and four alternatively spliced transcript variants encoding two distinct isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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