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Thermo Fisher Scientific APC Monoclonal Antibody (OTI1B12), TrueMAB
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APC 단백질을 인식하는 Mouse IgG1 단클론 항체로, IHC(P)에서 1:150 희석 비율로 사용 가능. 인간 시료 반응성, 액상 형태, Affinity chromatography로 정제됨. 종양 억제 단백질 연구 및 Wnt 신호 경로 분석에 적합.
- 판매단위
- pk
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마지막 업데이트 2025. 08. 04. 오후 08:24
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Thermo Fisher Scientific TA803682 APC Monoclonal Antibody (OTI1B12), TrueMAB 100 ul pk판매 단위 pk ·
재고 확인 필요
600,200원VAT 포함 660,220원
Thermo Fisher Scientific · Thermo Fisher Scientific APC Monoclonal Antibody (OTI1B12), TrueMAB
Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1B12 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 955–1382 of human APC produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in cell migration, adhesion, transcriptional activation, and apoptosis.
Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that can progress to malignancy.
Disease-associated mutations are often clustered in the mutation cluster region (MCR), resulting in truncated protein products.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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