Thermo Fisher Scientific LMNB2 Monoclonal Antibody (OTI2C6), TrueMAB
인간 LMNB2 단백질에 특이적인 단클론 항체로 Western blot에 최적화됨. Mouse IgG1 아이소타입이며, 액상 형태로 제공됨. 친화 크로마토그래피로 정제되었으며, PBS 기반 완충액에 보관. 연구용으로만 사용 가능.
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Applications
- Western Blot (WB): 1:2,000 dilution tested
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2C6 |
| Immunogen | Full length human recombinant protein of human LMNB2 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Nuclear lamins form a network of intermediate-type filaments at the nucleoplasmic side of the nuclear membrane. Two main subtypes of nuclear lamins can be distinguished: A-type lamins and B-type lamins.
A-type lamins include lamin A, lamin C, and lamin Adel10, while B-type lamins include lamin B1 and lamin B2.
Mutations in A-type lamins are associated with several rare dominant genetic disorders such as Emery-Dreifuss muscular dystrophy, dilated cardiomyopathy with conduction-system disease, and Dunnigan-type familial partial lipodystrophy.
A-type lamin expression correlates with cell differentiation, and as A-type lamins interact with chromatin, they are suggested to play a role in regulating differential gene expression.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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